Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.45 |
| ▸ | AR | P10275 | 3/20 | 0.45 |
| ▸ | PGR | P06401 | 3/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | SHBG | P04278 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10625546 | 1.00 | NFKB1 (0.56) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL9623669 | 0.90 | NFKB1 (0.56) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL17066183 | 0.89 | NR3C1 (0.57) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL10413147 | 0.88 | NFKB1 (0.55) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL11018967 | 0.84 | NR3C1 (0.46) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL8859719 | 0.83 | NFKB1 (0.61) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL8859749 | 0.82 | FNTA (0.54) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL9470074 | 0.82 | NFKB1 (0.60) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL10629876 | 0.82 | NFKB1 (0.67) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL10629868 | 0.82 | NFKB1 (0.67) | NFKB1NFKB2RELAKCNH2FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646136-A | ADMINISTERING STEROID HAVING ANGIOSTATIC ACTIVITY TO A PATIENT | DUKE UNIVERSITY (US) | 1997-07-08 | — | — | US | disclosed |