SCHEMBL8860059

SCHEMBL8860059

NC(Cc1ccc(O)cc1)[PH](=O)O

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.53
SLC6A2 P23975 1/20 0.53
SLC7A5 Q01650 1/20 0.53
ESR1 P03372 4/20 0.42
ESR2 Q92731 4/20 0.42
ABAT P80404 1/20 0.41
OPRK1 P41145 1/20 0.41
CA2 P00918 1/20 0.41
HDAC8 Q9BY41 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3862224 0.82 ALPI (0.53) TAAR1SLC6A2SLC7A5
SCHEMBL16836842 0.82 ALPI (0.53) TAAR1SLC6A2SLC7A5
Bromide SCHEMBL6929745 0.80 ALPI (0.52) TAAR1SLC6A2SLC7A5
SCHEMBL7350990 0.78 SLC6A4 (0.58) TAAR1
SCHEMBL1033973 0.76 SLC7A5 (0.49) TAAR1SLC6A2SLC7A5ESR1ESR2
Tyrosine SCHEMBL2541964 0.76 SLC7A5 (0.86) SLC7A5
Tyrosine SCHEMBL1033972 0.76 SLC7A5 (0.86) SLC7A5
SCHEMBL8014472 0.73 TAAR1 (0.67) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL15951398 0.73 TAAR1 (0.67) TAAR1SLC6A2SLC7A5ESR1ESR2
SCHEMBL22153161 0.72 OPRK1 (0.62) TAAR1SLC6A2SLC7A5ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997009333-A1 NOVEL THIO-PHOSPHOORGANIC COMPOUNDS WITH PLANT PROTECTING ACTIVITY SITRA FOUNDATION (FI) 1997-03-13 WO disclosed