Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.86 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.61 |
| ▸ | ALPI | P09923 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | XIAP | P98170 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TPH1 | P17752 | 1/20 | 0.53 |
| ▸ | GRB2 | P62993 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL2541964 | 1.00 | SLC7A5 (0.86) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL20787 | 0.93 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL11520041 | 0.93 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL10978805 | 0.93 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL11676395 | 0.93 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL1580 | 0.93 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL638520 | 0.93 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL1581 | 0.93 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL11676367 | 0.93 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL10978820 | 0.93 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114796520-A | anti-CD 74 antibody conjugates, compositions comprising anti-CD 74 antibody conjugates, and methods of use of anti-CD 74 antibody conjugates | 苏特罗生物制药公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-109069664-B | anti-CD 74 antibody conjugates, compositions comprising anti-CD 74 antibody conjugates, and methods of use of anti-CD 74 antibody conjugates | 苏特罗生物制药公司 | 2022-05-13 | — | — | CN | disclosed |
| EP-3401319-B1 | CELL CULTURE MEDIA | MERCK PATENT GMBH (DE) | 2020-07-22 | — | — | EP | disclosed |
| US-10619131-B2 | Cell culture media | MERCK PATENT GMBH (DE) | 2020-04-14 | — | — | US | disclosed |
| EP-3401319-A1 | CELL CULTURE MEDIA | Merck Patent GmbH (DE) | 2018-11-14 | — | — | EP | disclosed |
| US-10030225-B2 | Cell culture media | MERCK PATENT GMBH (DE) | 2018-07-24 | — | — | US | disclosed |
| EP-2920296-B1 | CELL CULTURE MED | MERCK PATENT GMBH (DE) | 2018-07-18 | — | — | EP | disclosed |
| CN-105120854-A | Novel salicylic acid derivatives, pharmaceutically acceptable salts thereof, compositions thereof, and methods of use thereof | UNIV TORONTO | 2015-12-02 | — | — | CN | disclosed |
| US-20150337258-A1 | CELL CULTURE MEDIA | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| EP-2920296-A1 | CELL CULTURE MED | Merck Patent GmbH (DE) | 2015-09-23 | — | — | EP | disclosed |
| CN-101217954-B | Substituted oxazole derivatives and their use as tyrosine kinase inhibitors | AB SCIENCE | 2013-07-10 | — | — | CN | disclosed |
| US-20110263535-A1 | TYROSINE-BASED PRODRUGS OF ANTIVIRAL AGENTS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2011-10-27 | — | — | US | disclosed |
| WO-2011133963-A2 | TYROSINE-BASED PRODRUGS OF ANTIVIRAL AGENTS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2011-10-27 | — | — | WO | disclosed |
| EP-2276510-A2 | CHEMICAL AND BIOCHEMICAL ADDUCTS AS BIOMARKERS FOR ORGANOPHOSPHATE EXPOSURE | Human Biomolecular Research Institute (US) | 2011-01-26 | — | — | EP | disclosed |
| WO-2010039163-A2 | CHEMICAL AND BIOCHEMICAL ADDUCTS AS BIOMARKERS FOR ORGANOPHOSPHATE EXPOSURE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2010-04-08 | — | — | WO | disclosed |
| CN-101217954-A | Substituted oxazole derivatives and their use as tyrosine kinase inhibitors | AB SCIENCE (FR) | 2008-07-09 | — | — | CN | disclosed |
| US-20030073850-A1 | 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use | ABBOTT LABORATORIES | 2003-04-17 | — | — | US | disclosed |
| EP-1259491-A1 | 4-IMIDAZOLE DERIVATIVES OF BENZYL AND RESTRICTED BENZYL SULFONAMIDES, SULFAMIDES, UREAS, CARBAMATES AND AMIDES AND THEIR USE AS ALPHA-1A AGONISTS | Abbott Laboratories (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001060802-A1 | 4-IMIDAZOLE DERIVATIVES OF BENZYL AND RESTRICTED BENZYL SULFONAMIDES, SULFAMIDES, UREAS, CARBAMATES, AND AMIDES AND THEIR USE AS ALPHA-1A AGONISTS | ABBOTT LABORATORIES (US) | 2001-08-23 | — | — | WO | disclosed |
| EP-0526488-A1 | BENZYLPHOSPHONIC ACID TYROSINE KINASE INHIBITORS. | PFIZER (US) | 1993-02-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150337258-A1 | CELL CULTURE MEDIA | SRC, PTPN4, PTPN6 | SLC7A5 423/4885PTGS1 1720/4885ALPI 4397/4885 |
| US-20030073850-A1 | 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use | ADRA1D, ADRB1, ADRA1A | SLC7A5 1841/4885PTGS1 467/4885ALPI 2322/4885 |
| US-10030225-B2 | Cell culture media | SRC, PTPN4, PTPN6 | SLC7A5 423/4885PTGS1 1720/4885ALPI 4397/4885 |
| US-10619131-B2 | Cell culture media | SRC, PTPN4, PTPN6 | SLC7A5 423/4885PTGS1 1720/4885ALPI 4397/4885 |
| US-20110263535-A1 | TYROSINE-BASED PRODRUGS OF ANTIVIRAL AGENTS | TYMP, MTAP, TK1 | SLC7A5 606/4885PTGS1 4608/4885ALPI 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.