Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3060452 | 0.98 | HPGD (0.48) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL2200249 | 0.92 | HPGD (0.47) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL6132882 | 0.88 | ALDH1A1 (0.42) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL4372871 | 0.88 | HPGD (0.56) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL3950467 | 0.85 | HPGD (0.52) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL3312314 | 0.83 | ALDH1A1 (0.42) | HPGDALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL8655587 | 0.81 | HPGD (0.39) | HPGDALDH1A1TSHRHSD11B1HTT | |
| SCHEMBL2202337 | 0.78 | ALDH1A1 (0.41) | HPGDALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3920347 | 0.74 | HPGD (0.41) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL3557212 | 0.72 | HPGD (0.38) | HPGDALDH1A1TSHRHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658926-A | ANTICOAGULANTS, ANTIHISTAMINES, ANTIARRHYTHMIC, CARTIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5506239-A | Carbostyril derivative and platelets aggregation inhibitory agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0569592-A1 | CARBOSTYRIL DERIVATIVE AND PLATELET AGGLUTINATION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-18 | — | — | EP | disclosed |