Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200249 | 0.96 | HPGD (0.47) | ALDH1A1HPGDTSHRLMNAHTT | |
| SCHEMBL3060452 | 0.90 | HPGD (0.48) | ALDH1A1HPGDTSHRHTTSMN1; SMN2 | |
| SCHEMBL8860937 | 0.88 | HPGD (0.52) | ALDH1A1HPGDTSHRLMNAHTT | |
| SCHEMBL2202337 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL3950467 | 0.81 | HPGD (0.52) | ALDH1A1HPGDTSHRHTTSMN1; SMN2 | |
| SCHEMBL3312314 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HPGDTSHRLMNASMN1; SMN2 | |
| SCHEMBL4372871 | 0.79 | HPGD (0.56) | ALDH1A1HPGDTSHRLMNAHTT | |
| SCHEMBL3913964 | 0.73 | HPGD (0.46) | ALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL3911205 | 0.73 | HPGD (0.42) | ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL3552654 | 0.72 | CHRNB2 (0.36) | ALDH1A1HPGDTSHRLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | claimed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | claimed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | claimed |
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |