Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29599774 | 1.00 | EGFR (0.41) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| Hydrochloric Acid SCHEMBL29733094 | 0.97 | EGFR (0.39) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| Hydrochloric Acid SCHEMBL29733087 | 0.97 | EGFR (0.39) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1285336 | 0.70 | ALDH1A1 (0.39) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL3831708 | 0.70 | — | — | |
| SCHEMBL4937147 | 0.70 | ALDH1A1 (0.39) | MAPTALDH1A1ACHETSHRMAPK14 | |
| Strinoline SCHEMBL11278670 | 0.69 | GPR3 (0.44) | EGFRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL3819567 | 0.69 | — | — | |
| SCHEMBL8401811 | 0.69 | PIK3CG (0.47) | EGFRMAPTALDH1A1MAP4K4DYRK1A | |
| SCHEMBL6028972 | 0.69 | NQO2 (0.43) | MAPTALDH1A1MAP4K4PIM1RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 671 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634953-B1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS INC (US) | 2024-01-03 | — | — | EP | claimed |
| CN-117186155-A | Organic electroluminescent material and device | 环球展览公司 | 2023-12-08 | — | — | CN | claimed |
| CN-116969901-A | Preparation method of 1,2,4-benzotriazine derivative | 浙江师范大学 | 2023-10-31 | — | — | CN | claimed |
| CN-116905240-A | Automobile skylight composite fabric and preparation method thereof | 金华市华尔汽车饰件有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-114957145-B | 1,2,4-benzotriazine derivative and preparation method thereof | 浙江师范大学 | 2023-07-18 | — | — | CN | claimed |
| CN-114957145-A | 1,2,4-benzotriazine derivative and preparation method thereof | 浙江师范大学 | 2022-08-30 | — | — | CN | claimed |
| US-11285165-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2022-03-29 | — | — | US | claimed |
| EP-3305778-B1 | INHIBITORS OF PLASMA KALLIKREIN | KALVISTA PHARMACEUTICALS LTD (GB) | 2022-01-19 | — | — | EP | claimed |
| EP-2872161-B1 | DIANHYDROGALACTITOL FOR USE IN TREATING TYROSINE-KINASE-INHIBITOR-RESISTANT MALIGNANCIES IN PATIENTS WITH GENETIC POLYMORPHISMS OR AHI1 DYSREGULATIONS OR MUTATIONS | DEL MAR PHARMACEUTICALS (CA) | 2020-12-16 | — | — | EP | claimed |
| EP-3305778-A1 | INHIBITORS OF PLASMA KALLIKREIN | Kalvista Pharmaceuticals Limited (GB) | 2018-04-11 | — | — | EP | claimed |
| US-5631253-A | FUNGICIDES, INSECTICIDES AND MITICIDES USING METHYLOXIME PHENYLPROPENOIC ACID | ZENECA LIMITED (GB) | 1997-05-20 | — | — | US | claimed |
| EP-0145337-B1 | ELECTROCHROMIC DEVICES | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1990-08-08 | — | — | EP | claimed |
| EP-0096723-B1 | BATTERIES FABRICATED WITH ELECTROACTIVE POLYMERS | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1988-08-10 | — | — | EP | claimed |
| EP-0137832-B1 | PHARMACEUTICAL COMPOSITIONS OF ANTI-PANCREATIC INFLAMMATORY EFFECT | BIOGAL GYOGYSZERGYAR (HU) | 1987-08-12 | — | — | EP | claimed |
| US-4613211-A | REVERSE COLOR CHANGING POLYMER FILM AS DISPLAY ELECTRODE | CHEVRON RESEARCH COMPANY (US) | 1986-09-23 | — | — | US | claimed |
| US-4579679-A | Electroactive polymers | CHEVRON RESEARCH COMPANY (US) | 1986-04-01 | — | — | US | claimed |
| EP-0145337-A2 | Electrochromic devices | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1985-06-19 | — | — | EP | claimed |
| EP-0096723-A1 | BATTERIES FABRICATED WITH ELECTROACTIVE POLYMERS. | CHEVRON RES (US) | 1983-12-28 | — | — | EP | claimed |
| WO-1983002368-A1 | BATTERIES FABRICATED WITH ELECTROACTIVE POLYMERS | CHEVRON RES (US) | 1983-07-07 | — | — | WO | claimed |
| US-4316022-A | Benzo-as-triazine derivatives | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-02-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11285165-B2 | Selective high-affinity polydentate ligands and methods of making such | CD44, FCGR3B, FCGR2A | EGFR 384/4885PI4KA 3466/4885PI4K2B 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.