SCHEMBL8863371

SCHEMBL8863371

O=C(c1cncnc1)N1CCC(N2CCC(N3C(=O)NCc4ccccc43)CC2)CC1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OXTR P30559 1/20 0.54
AVPR1A P37288 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3959841 0.77 OXTR (0.53) OXTRAVPR1A
SCHEMBL8863377 0.76 OXTR (0.50) OXTRAVPR1A
Hydrochloric Acid SCHEMBL8863969 0.76 OPRM1 (0.51) OXTRAVPR1A
SCHEMBL8863734 0.72 CHRM1 (0.69)
SCHEMBL9058671 0.71 L3MBTL3 (0.39)
SCHEMBL6247351 0.71 OXTR (0.53) OXTRAVPR1A
SCHEMBL13801271 0.70 OXTR (0.46) OXTRAVPR1A
SCHEMBL7442515 0.69 OXTR (0.72) OXTRAVPR1A
SCHEMBL5768740 0.68 HTR2C (0.48) OXTRAVPR1A
SCHEMBL14410177 0.68 OXTR (0.47) OXTRAVPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996013262-A1 MUSCARINE ANTAGONISTS MERCK & CO., INC. (US) 1996-05-09 WO claimed
US-5691323-A BENZIMIDAZOL-2-ONES MERCK & CO., INC. (US) 1997-11-25 US disclosed
US-5574044-A BENZIMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF MYOPIA MERCK & CO., INC. (US) 1996-11-12 US disclosed
WO-1996013262-A1 MUSCARINE ANTAGONISTS MERCK & CO., INC. (US) 1996-05-09 WO disclosed