Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4137306 | 0.89 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL23668209 | 0.83 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL23668208 | 0.81 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL27801908 | 0.81 | KCNH2 (0.52) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL27627421 | 0.81 | CYP17A1 (0.38) | ALDH1A1RAB9ASMN1; SMN2LMNANPC1 | |
| SCHEMBL29349003 | 0.79 | ESR1 (0.50) | ALDH1A1L3MBTL1 | |
| SCHEMBL28445159 | 0.79 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL11811765 | 0.77 | ENPP2 (0.44) | CALM1LMNAPKM | |
| SCHEMBL12419351 | 0.75 | ALDH1A1 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL29349002 | 0.75 | LTA4H (0.48) | ALDH1A1L3MBTL1RAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028646-A | Nitrogen-containing heterocyclic compound, preparation method and application in antitumor preparation | 山东第一医科大学(山东省医学科学院) | 2022-09-09 | — | — | CN | claimed |
| CN-111718361-B | Metal beta-lactamase inhibitor and preparation method and application thereof | 南京工业大学 | 2022-04-05 | — | — | CN | claimed |
| CN-111718361-A | Metal beta-lactamase inhibitor and preparation method and application thereof | 南京工业大学 | 2020-09-29 | — | — | CN | claimed |
| JP-4657605-B2 | — | — | 2011-03-23 | — | — | JP | claimed |
| JP-2007534719-A | — | — | 2007-11-29 | — | — | JP | claimed |
| EP-1742925-A1 | SUBSTITUTED 5, 6, 7, 8-TETRAHYDRO-PYRIDO[4, 3-D]PYRIMIDINE-2-YL COMPOUNDS AND 5, 6, 7, 8-TETRAHYDRO-QUINAZOLINE-2-YL COMPOUNDS | Grünenthal GmbH (DE) | 2007-01-17 | — | — | EP | claimed |
| WO-2005105759-A1 | SUBSTITUTED 5, 6, 7, 8-TETRAHYDRO-PYRIDO[4, 3-D]PYRIMIDINE-2-YL COMPOUNDS AND 5, 6, 7, 8-TETRAHYDRO-QUINAZOLINE-2-YL COMPOUNDS | Grünenthal GmbH (DE) | 2005-11-10 | — | — | WO | claimed |
| JP-2005515997-A | — | — | 2005-06-02 | — | — | JP | claimed |
| EP-1451154-A2 | INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2 | Wyeth (US) | 2004-09-01 | — | — | EP | claimed |
| WO-2003048122-A2 | INHIBITORS OF CYTOSOLIC PHOSPHOLIPASE A2 | WYETH (US) | 2003-06-12 | — | — | WO | claimed |
| CN-115028646-A | Nitrogen-containing heterocyclic compound, preparation method and application in antitumor preparation | 山东第一医科大学(山东省医学科学院) | 2022-09-09 | — | — | CN | disclosed |
| CN-111718361-B | Metal beta-lactamase inhibitor and preparation method and application thereof | 南京工业大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-111718361-A | Metal beta-lactamase inhibitor and preparation method and application thereof | 南京工业大学 | 2020-09-29 | — | — | CN | disclosed |
| CN-109053693-A | The preparation and its application of pyridazine aminated compounds | 周银平 | 2018-12-21 | — | — | CN | disclosed |
| EP-3068225-A1 | COMPOSITION OF 1,5-DIMETHYL-6-THIOXO-3-(2,2,7-TRIFLUORO-3-OXO-4-(PROP-2-YNYL)-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZIN-6-YL)-1,3,5-TRIAZINANE-2,4-DIONE | BASF SE (DE) | 2016-09-21 | — | — | EP | disclosed |
| WO-1998029392-A1 | SUBSTITUTED 4-BENZOYL-PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-07-09 | — | — | WO | disclosed |
| WO-1998029383-A1 | 3-AMINOCARBONYL/3-AMINOTHIOCARBONYL-SUBSTITUTED 2-BENZOYL- CYCLOHEXAN-1,3-DIONES WITH HERBICIDAL EFFECT | BASF AKTIENGESELLSCHAFT (DE) | 1998-07-09 | — | — | WO | disclosed |
| EP-0846113-A1 | 1-(PYRIDYL)-PYRAZOLS AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997038987-A1 | HERBICIDAL BENZOYLISOTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-23 | — | — | WO | disclosed |
| WO-1997007114-A1 | 1-(PYRIDYL)-PYRAZOLS AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-02-27 | — | — | WO | disclosed |