SCHEMBL8863550

SCHEMBL8863550

CCN1CCOC1c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.45
PRCP P42785 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
DRD2 P14416 3/20 0.41
DRD1 P21728 2/20 0.40
DRD3 P35462 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
CHRM3 P20309 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
SLC6A4 P31645 1/20 0.39
HRH1 P35367 1/20 0.39
OPRM1 P35372 1/20 0.39
OPRK1 P41145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22157934 0.84 ALDH1A1 (0.43) DRD2DRD1DRD3SMN1; SMN2ALDH1A1
SCHEMBL22122581 0.83 DRD2 (0.44) HTR1AL3MBTL1DRD2DRD1DRD3
SCHEMBL22157933 0.82 DRD3 (0.42) DRD2DRD1DRD3ALDH1A1HTR2A
SCHEMBL22129534 0.81 TP53 (0.45) HTR1AL3MBTL1DRD2CYP2D6
SCHEMBL24982149 0.80 HPGD (0.42) L3MBTL1DRD2DRD1SMN1; SMN2ALDH1A1
SCHEMBL24217664 0.80 DRD2 (0.47) DRD2DRD3SMN1; SMN2SLC6A2SLC6A4
SCHEMBL6446078 0.79 SLC18A3 (0.50) HTR1AL3MBTL1DRD2SMN1; SMN2ALDH1A1
SCHEMBL10123770 0.79 HTR1A (0.63) HTR1APRCPDRD2DRD1SMN1; SMN2
SCHEMBL6444637 0.79 SLC18A3 (0.41) HTR1AL3MBTL1SMN1; SMN2ALDH1A1CHRM2
SCHEMBL24217662 0.78 HTR2A (0.38) PRCPL3MBTL1DRD2DRD1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60155114-A None JP disclosed
JP-63264411-A None JP disclosed
EP-3898619-B1 MOISTURE-CURABLE POLYURETHANE COMPOSITION CONTAINING OXAZOLIDINE SIKA TECH AG (CH) 2023-02-08 EP disclosed
US-20220025176-A1 MOISTURE-CURING POLYURETHANE COMPOSITION CONTAINING OXAZOLIDINE SIKA TECHNOLOGY AG (CH) 2022-01-27 US disclosed
EP-3898619-A1 MOISTURE-CURING POLYURETHANE COMPOSITION CONTAINING OXAZOLIDINE Sika Technology AG (CH) 2021-10-27 EP disclosed
WO-2020126841-A1 MOISTURE-CURING POLYURETHANE COMPOSITION CONTAINING OXAZOLIDINE SIKA TECHNOLOGY AG (CH) 2020-06-25 WO disclosed
US-5639400-A CONTAINS A OXAZOLINE COMPOUND AS A STABILIZER TO REDUCE THE DECLINE OF PHOTOSTIMULATED LUMINESCENCE INTENSITIES OF STORAGE PHOSPHOR EASTMAN KODAK COMPANY (US) 1997-06-17 US disclosed
JP-S63264411-A CARCINOSTATIC AGENT RIKAGAKU KENKYUSHO 1988-11-01 JP disclosed
JP-S60155114-A CARCINOSTATIC AGENT RIKAGAKU KENKYUSHO 1985-08-15 JP disclosed