SCHEMBL88637

SCHEMBL88637

C=CCN(CC=C)c1ccc(C(=O)c2ccc(N(CC=C)CC=C)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPT P10636 1/20 0.52
LMNA P02545 1/20 0.46
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
LSS P48449 8/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
PTPN1 P18031 2/20 0.43
CHKA P35790 1/20 0.40
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1521415 0.93 RAB9A (0.58) HPGDALDH1A1MAPTLMNARAB9A
SCHEMBL9640200 0.90 HPGD (0.43) HPGDALDH1A1MAPTLMNARAB9A
SCHEMBL11391579 0.88 HPGD (0.44) HPGDALDH1A1MAPTLMNARAB9A
SCHEMBL250420 0.86 TSHR (0.46) ALDH1A1RAB9ANPC1SMN1; SMN2PTPN1
SCHEMBL4564604 0.85 MAPT (0.50) HPGDALDH1A1MAPTLMNARAB9A
SCHEMBL5950655 0.85 KDM4E (0.47) HPGDALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL851567 0.82 CHKA (0.50) ALDH1A1SMN1; SMN2PTPN1CHKATSHR
SCHEMBL11399468 0.82 AKR1C3 (0.54) HPGDALDH1A1LMNARAB9ANPC1
SCHEMBL8999586 0.82 LIG1 (0.54) HPGDALDH1A1MAPTLMNARAB9A
SCHEMBL8582159 0.82 HPGD (0.40) HPGDALDH1A1MAPTLMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 689 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080138743-A1 Laser sensitive lithographic printing plate having specific photopolymer composition TENG GARY GANGHUI 2008-06-12 US claimed
US-20080118869-A1 Laser sensitive lithographic printing plate having specific photopolymer composition TENG GARY G 2008-05-22 US claimed
US-7348132-B2 Laser sensitive lithographic printing plate having specific photopolymer composition TENG GARY GANGHUI 2008-03-25 US claimed
EP-0890587-B1 Amine-initiated elastomers having a hysteresis reducing interaction with silica BRIDGESTONE CORP (JP) 2008-03-05 EP claimed
US-20070172765-A1 Laser sensitive lithographic printing plate having specific photopolymer composition TENG GARY G 2007-07-26 US claimed
US-20060084176-A1 Detection of uronium salts YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-04-20 US claimed
EP-0890586-B1 Composition of cyclic amine-initiated elastomers and silica and process for the production thereof BRIDGESTONE CORP (JP) 2004-09-15 EP claimed
US-5916961-A AMINE-CONTAINING LITHIUM INITIATOR, AMINE TERMINATING AGENT, AMINE FUNCTIONIZED POLYMER BRIDGESTONE CORPORATION (JP) 1999-06-29 US claimed
US-5866650-A Composition of cyclic amine-initiated elastomers and amorphous silica and process for the production thereof BRIDGESTONE CORPORATION (JP) 1999-02-02 US claimed
EP-0890587-A1 Amine-initiated elastomers having a hysteresis reducing interaction with silica Bridgestone Corporation (JP) 1999-01-13 EP claimed
EP-0890586-A1 Composition of cyclic amine-initiated elastomers and silica and process for the production thereof Bridgestone Corporation (JP) 1999-01-13 EP claimed
US-5576138-A MIXTURE OF RESIN, PHOTOSENSITIZER AND BENZOPHENONE COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 1996-11-19 US claimed
US-5478692-A Fine patterning for electronics TOKYO OHKA KOGYO CO., LTD. (JP) 1995-12-26 US claimed
US-5030548-A Photoiniator system comprising a 4,4'-bis(dialkylamino) benzophenone, an aromatic ketone and lophine dimer; also present a halogen compound leuco and dye; lithography; printing plates; photoresists FUJI PHOTO FILM CO., LTD. (JP) 1991-07-09 US claimed
EP-0137228-B1 PHOTOPOLYMERIZABLE COMPOSITION FUJI PHOTO FILM CO., LTD. (JP) 1988-10-05 EP claimed
US-4661434-A PHOTORESISTS FUJI PHOTO FILM CO., LTD. (JP) 1987-04-28 US claimed
US-4548892-A INITIATOR FOR ADDITION POLYMERS FUJI PHOTO FILM CO., LTD. (JP) 1985-10-22 US claimed
EP-0137228-A2 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1985-04-17 EP claimed
JP-7248621-A None JP disclosed
JP-S06224240-A 0001-01-01 JP disclosed