Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.54 |
| ▸ | CDC25B | P30305 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521415 | 0.86 | RAB9A (0.58) | ATMALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8999586 | 0.85 | LIG1 (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11132905 | 0.83 | LMNA (0.39) | ALDH1A1SMN1; SMN2L3MBTL1HPGDLMNA | |
| SCHEMBL88637 | 0.82 | HPGD (0.52) | ALDH1A1SMN1; SMN2HPGDLMNANPC1 | |
| SCHEMBL250420 | 0.81 | TSHR (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL3854600 | 0.81 | KMT2A (0.70) | AKR1C3CDC25BCDC25AHSD17B10ALDH1A1 | |
| SCHEMBL1977600 | 0.80 | MEN1 (0.65) | AKR1C3CDC25BATMNR4A1CDC25A | |
| SCHEMBL11767364 | 0.79 | AKR1C3 (0.44) | AKR1C3CDC25BATMNR4A1CDC25A | |
| SCHEMBL28278314 | 0.79 | HPGD (0.47) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL701316 | 0.78 | HPGD (0.70) | AKR1C3CDC25BATMNR4A1CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255577-A | Process and intermediates for preparing 3-[4-(disubstituted-amino)phenyl] or | STERLING DRUG INC. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4200313-A | Carbonless duplicating systems | STERLING DRUG INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4187223-A | 3-[4-(Disubstituted-amino)phenyl]-3-(diphenylamino)phthalides | STERLING DRUG INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4168378-A | THERMOGRAPHY, LEUCO DYES | STERLING DRUG INC. (US) | 1979-09-18 | — | — | US | disclosed |