Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911503 | 0.87 | CHRM1 (0.40) | CHRM1L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8116548 | 0.76 | CHRM1 (0.41) | CHRM1L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6608431 | 0.76 | CHRM1 (0.36) | CHRM1SMN1; SMN2CHRNA4 | |
| SCHEMBL8864052 | 0.76 | MAPT (0.43) | CHRM1MAPT | |
| SCHEMBL10283737 | 0.74 | — | — | |
| SCHEMBL8124258 | 0.73 | CHRM1 (0.40) | CHRM1L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3253559 | 0.72 | — | — | |
| SCHEMBL441859 | 0.72 | — | — | |
| SCHEMBL3154091 | 0.72 | — | — | |
| SCHEMBL3154694 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622953-A | DRUG RESISTANT TO ANTICANCER CHEMOTHERAPEUTIC DRUG | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |