SCHEMBL8922858

SCHEMBL8922858

COc1ccc(O)c2ccc(C3CCCCC3)cc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
QDPR P09417 2/20 0.50
ACMSD Q8TDX5 2/20 0.47
TSHR P16473 1/20 0.43
PDE4B Q07343 4/20 0.43
PDE4A P27815 3/20 0.43
PDE4C Q08493 3/20 0.43
PDE4D Q08499 3/20 0.43
CA2 P00918 2/20 0.43
NR3C1 P04150 1/20 0.43
PTPN7 P35236 2/20 0.41
DUSP3 P51452 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
ALOX5 P09917 1/20 0.39
PTPN1 P18031 1/20 0.39
PPARG P37231 1/20 0.39
PPARD Q03181 1/20 0.39
CNR2 P34972 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9278504 0.90 QDPR (0.42) QDPRACMSDTSHRPDE4BPDE4A
SCHEMBL8864091 0.83 QDPR (0.69) QDPRACMSDTSHRCA2NR3C1
SCHEMBL9325871 0.77 PDE4A (0.59) QDPRPDE4BPDE4APDE4CPDE4D
SCHEMBL8922499 0.77 ACMSD (0.47) QDPRACMSD
SCHEMBL7723660 0.74 PDE4B (0.49) QDPRTSHRPDE4BPDE4APDE4C
SCHEMBL11130424 0.74 QDPR (0.76) QDPRTSHRCA2NR3C1ALDH1A1
SCHEMBL16918772 0.74 TUBB4A (0.57) QDPRPDE4BPDE4APDE4CPDE4D
SCHEMBL11694411 0.73 QDPR (0.50) QDPRACMSDTSHRPDE4BPDE4A
SCHEMBL11875043 0.73 QDPR (0.50) QDPRACMSDTSHRPDE4BPDE4A
SCHEMBL1264565 0.73 TUBB4A (0.53) QDPRPDE4BPDE4APDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330504-B1 Photosensitive material and image forming method CANON KK (JP) 1996-05-22 EP claimed
EP-0653680-A2 Photosensitive composition, photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-05-17 EP claimed
US-5663032-A NAPHTHOL DERIVATIVE REDUCING AGENT CANON KABUSHIKI KAISHA (JP) 1997-09-02 US disclosed
EP-0332455-B1 Photosensitive material and image forming method CANON KK (JP) 1996-06-05 EP disclosed
EP-0330504-B1 Photosensitive material and image forming method CANON KK (JP) 1996-05-22 EP disclosed
EP-0360014-B1 Photosensitive material and image forming method using same CANON KK (JP) 1996-01-03 EP disclosed
US-5415974-A Silver halide, organic silver salt, polymerizable compound, heat-diffusing dye CANON KABUSHIKI KAISHA (JP) 1995-05-16 US disclosed
US-5260164-A Silver halide, organic silver salt, cyclic reducing agent, the above compounds adapted to provide imagewise oxidized product of reducing agent upon imagewise exposure and heat development, polymer precursor, photopolymerization initiator CANON KABUSHIKI KAISHA (JP) 1993-11-09 US disclosed
US-5064744-A Heat, photopolymerization, silver halide contrast CANON KABUSHIKI KAISHA (JP) 1991-11-12 US disclosed
US-5041369-A Silver Halide, Silver Salt, Reducing Agent, Metal or Organic Dye CANON KABUSHIKI KAISHA (JP) 1991-08-20 US disclosed
EP-0360014-A1 Photosensitive material and image forming method using same CANON KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed
EP-0332455-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1989-09-13 EP disclosed
EP-0330504-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1989-08-30 EP disclosed
EP-0326424-A2 Photosensitive composition, photosensitive material, and image forming method CANON KABUSHIKI KAISHA (JP) 1989-08-02 EP disclosed