Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | P4HB | P07237 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554199 | 0.84 | P4HB (0.59) | POLBMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8864727 | 0.84 | P4HB (0.59) | POLBMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL9081995 | 0.79 | CA12 (0.64) | ALDH1A1SMN1; SMN2MAPTCA12CA1 | |
| SCHEMBL9312488 | 0.79 | CA2 (0.64) | POLBKMT2AALDH1A1TDP1LMNA | |
| SCHEMBL71224 | 0.78 | CA12 (0.84) | MEN1KMT2AALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL5057418 | 0.78 | CA12 (0.84) | MEN1KMT2AALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL28041658 | 0.77 | CA2 (0.62) | KMT2AALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL28435747 | 0.77 | CA2 (0.62) | POLBKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28207122 | 0.77 | CA2 (0.62) | KMT2AALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL19122351 | 0.77 | CA2 (0.62) | POLBKMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624922-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1997-04-29 | — | — | US | disclosed |