Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 5/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014230 | 1.00 | GPR119 (0.38) | GPR119LMNAMAPK1RAB9ANR1D1 | |
| SCHEMBL6397569 | 1.00 | GPR119 (0.38) | GPR119LMNAMAPK1RAB9ANR1D1 | |
| SCHEMBL6401112 | 0.90 | GPR119 (0.41) | GPR119LMNAMAPK1RAB9ANR1D1 | |
| SCHEMBL6398512 | 0.86 | LMNA (0.37) | GPR119LMNAMAPK1RAB9AGAA | |
| SCHEMBL8865061 | 0.82 | GPR119 (0.38) | GPR119LMNAMAPK1RAB9ANR1D1 | |
| SCHEMBL6402328 | 0.82 | GPR119 (0.38) | GPR119LMNAMAPK1RAB9ANR1D1 | |
| SCHEMBL8864939 | 0.82 | GPR119 (0.38) | GPR119LMNAMAPK1RAB9ANR1D1 | |
| SCHEMBL2932359 | 0.81 | GAA (0.38) | GPR119LMNAMAPK1RAB9ANR1D1 | |
| SCHEMBL2087756 | 0.81 | GAA (0.38) | GPR119LMNAMAPK1RAB9ANR1D1 | |
| SCHEMBL9020481 | 0.79 | NR1D1 (0.36) | GPR119LMNAMAPK1RAB9ANR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672701-A | 4-substituted alkyl carbapenem antibiotics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| CN-1030918-C | 4-substituted alkyl carbapenem antibiotics | BRISTOL MYERS SQUIBB CO (US) | 1996-02-07 | — | — | CN | disclosed |
| EP-0433759-A1 | 4-Substituted alkyl carbapenem antibiotics | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | disclosed |