Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10533216 | 0.93 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL4975385 | 0.85 | CES2 (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL8604199 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2MAPTALOX15 | |
| SCHEMBL28440125 | 0.83 | KDM4E (0.48) | ALDH1A1KDM4EMAPTPOLBCYP2C19 | |
| SCHEMBL279655 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL8297060 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL31107414 | 0.80 | KDM4E (0.52) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL4087542 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL5852958 | 0.80 | KDM4E (0.52) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL7596837 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |
| US-5631309-A | MIXTURE OF DYE AND POLYMER WHICH CAN UNDERGO DECARBOXYLATION; WATERPROOFING; NONSCORCHING AND NONSTICKING | KAO CORPORATION (JP) | 1997-05-20 | — | — | US | disclosed |