Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HTR2B | P41595 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864617 | 0.83 | KCNH2 (0.52) | SLC6A2SLC6A4SLC6A3KCNH2GAA | |
| SCHEMBL8557736 | 0.79 | KCNH2 (0.83) | SLC6A2SLC6A4SLC6A3KCNH2NOS3 | |
| SCHEMBL8554225 | 0.77 | KCNH2 (0.83) | SLC6A2SLC6A4SLC6A3KCNH2HTR2A | |
| Hydrochloric Acid SCHEMBL8864724 | 0.76 | KCNH2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2NOS3 | |
| SCHEMBL11018524 | 0.71 | HTR2A (0.44) | SLC6A2SLC6A4SLC6A3KCNH2NOS3 | |
| SCHEMBL8864634 | 0.71 | KCNH2 (0.40) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL8864666 | 0.71 | KCNH2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2KDM4E | |
| Hydrochloric Acid SCHEMBL8557094 | 0.71 | KCNH2 (0.60) | SLC6A2SLC6A4SLC6A3KCNH2NOS3 | |
| SCHEMBL8558645 | 0.71 | KCNH2 (0.72) | SLC6A2SLC6A4SLC6A3KCNH2PRCP | |
| SCHEMBL8555627 | 0.71 | KCNH2 (0.72) | SLC6A2SLC6A4SLC6A3KCNH2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624922-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0597540-B1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC (US) | 1996-06-05 | — | — | EP | disclosed |
| US-5380721-A | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0597540-A1 | Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents | STERLING WINTHROP INC. (US) | 1994-05-18 | — | — | EP | disclosed |