Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865251 | 0.90 | CYP3A4 (0.39) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865583 | 0.85 | ALOX5 (0.38) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865464 | 0.84 | CYP3A4 (0.49) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8890100 | 0.83 | CYP3A4 (0.52) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865150 | 0.81 | RARA (0.58) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8874466 | 0.81 | CYP26A1 (0.38) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8875274 | 0.78 | CYP3A4 (0.41) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8661571 | 0.77 | CYP3A4 (0.43) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8875128 | 0.76 | CYP3A4 (0.40) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL8865783 | 0.76 | RARA (0.33) | CYP3A4RARARARBRARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677323-A | SKIN DISORDERS, PSORIASIS | ALLERGAN (US) | 1997-10-14 | — | — | US | disclosed |