Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27773277 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1HPGDCRBN | |
| SCHEMBL7102993 | 0.72 | MEN1 (0.37) | KDM4E | |
| SCHEMBL8865619 | 0.72 | CYP3A4 (0.45) | KDM4EALDH1A1 | |
| SCHEMBL10681803 | 0.65 | KDM4E (0.46) | KDM4EALDH1A1HPGDACHECA1 | |
| SCHEMBL7608467 | 0.65 | HTR6 (0.31) | — | |
| SCHEMBL8866074 | 0.65 | ADRA1A (0.45) | KDM4EALDH1A1HPGD | |
| SCHEMBL7103836 | 0.65 | TDP1 (0.35) | ALDH1A1HPGD | |
| SCHEMBL29021937 | 0.64 | PDGFRB (0.47) | KDM4EALDH1A1HPGD | |
| SCHEMBL2096746 | 0.64 | METAP2 (0.51) | ALDH1A1HPGDCA1CA2CA4 | |
| SCHEMBL26259644 | 0.64 | HIF1A (0.41) | KDM4EALDH1A1HPGDACHECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1054376-C | Substituted 1H-imidazoles | UCB SA (BE) | 2000-07-12 | — | — | CN | disclosed |
| US-5658938-A | HYPOTENSIVE AGENT, ANTIISCHMIC AGENTS | U C B S.A. (BE) | 1997-08-19 | — | — | US | disclosed |
| CN-1133837-A | Substituted 1H-imidazoles | UCB SA (BE) | 1996-10-23 | — | — | CN | disclosed |
| EP-0717037-A1 | Substituted 1H-imidazoles having alpha 2-agonistic and alpha 1-antagonistic activity | U C B, S.A. (BE) | 1996-06-19 | — | — | EP | disclosed |