Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865356 | 1.00 | PTPN1 (0.50) | PTPN1GSK3BDPEP1CYP1A2AKR1C3 | |
| SCHEMBL9903274 | 0.83 | EPHX2 (0.56) | PTPN1DPEP1CYP1A2AKR1C3HDAC3 | |
| SCHEMBL9903269 | 0.83 | EPHX2 (0.56) | PTPN1DPEP1CYP1A2AKR1C3HDAC3 | |
| SCHEMBL16969112 | 0.81 | AKR1C3 (0.47) | DPEP1CYP1A2AKR1C3PSEN1PSEN2 | |
| SCHEMBL7982768 | 0.79 | CYP3A4 (0.47) | PTPN1GSK3BAKR1C3EPHX2PPARG | |
| SCHEMBL6743009 | 0.79 | CYP3A4 (0.47) | PTPN1GSK3BAKR1C3EPHX2PPARG | |
| SCHEMBL6743003 | 0.79 | CYP3A4 (0.47) | PTPN1GSK3BAKR1C3EPHX2PPARG | |
| SCHEMBL8041928 | 0.78 | CYP3A4 (0.63) | PTPN1GSK3BAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL781849 | 0.78 | CYP3A4 (0.63) | PTPN1GSK3BAKR1C3CYP3A4CYP2C9 | |
| SCHEMBL4327979 | 0.78 | CYP3A4 (0.63) | PTPN1GSK3BAKR1C3CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646313-A | PREPARING ENKEPHALINASE INHIBITORS | SOCIETE CIVILE BIOPROJET (FR) | 1997-07-08 | — | — | US | disclosed |
| US-5612371-A | ENZYME INHIBITORS | SOCIETE CIVILE BIOPROJECT (FR) | 1997-03-18 | — | — | US | disclosed |