Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23111386 | 0.87 | TSHR (0.46) | TSHRSMN1; SMN2MAPTKMT2AHRH4 | |
| SCHEMBL21570876 | 0.82 | TSHR (0.48) | TSHRSMN1; SMN2MAPTKMT2AHRH4 | |
| SCHEMBL8928159 | 0.82 | ACHE (0.48) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL13836286 | 0.82 | ACHE (0.50) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL5497627 | 0.81 | TSHR (0.45) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL4458944 | 0.80 | ACHE (0.47) | TSHRSMN1; SMN2MAPTALDH1A1ACHE | |
| SCHEMBL4746818 | 0.79 | SMN1; SMN2 (0.46) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28740453 | 0.78 | TSHR (0.39) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL27605571 | 0.78 | SMN1; SMN2 (0.42) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL12544682 | 0.77 | TSHR (0.38) | TSHRSMN1; SMN2MAPTKMT2AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672701-A | 4-substituted alkyl carbapenem antibiotics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-30 | — | — | US | disclosed |