Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 5/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8866836 | 0.83 | F11 (0.40) | F11KLKB1DPP4DPP7WDR5 | |
| Trifluoroacetic Acid SCHEMBL8867001 | 0.77 | DPP4 (0.37) | F11KLKB1DPP4DPP7WDR5 | |
| SCHEMBL8866508 | 0.75 | ACACB (0.56) | — | |
| Hydrochloric Acid SCHEMBL20337635 | 0.73 | LMNA (0.34) | WDR5RAB9ALMNANPC1HTT | |
| SCHEMBL5308583 | 0.73 | LMNA (0.41) | WDR5RAB9ALMNANPC1HTT | |
| Trifluoroacetic Acid SCHEMBL8866066 | 0.71 | GCGR (0.40) | GCGRGIPR | |
| SCHEMBL8866699 | 0.71 | WDR5 (0.48) | WDR5GCGR | |
| SCHEMBL8866516 | 0.70 | WDR5 (0.40) | DPP4DPP7WDR5RAB9ALMNA | |
| Trifluoroacetic Acid SCHEMBL9233799 | 0.69 | HDAC4 (0.38) | F10 | |
| SCHEMBL20337612 | 0.69 | RPS6KA5 (0.37) | WDR5LMNAHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |