Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17164088 | 0.70 | PARP10 (0.48) | FAAHKDM4ESMN1; SMN2MAOBPARP10 | |
| SCHEMBL8552703 | 0.67 | DRD2 (0.42) | PLA2G7FAAHHTTMEN1KMT2A | |
| SCHEMBL27734525 | 0.67 | PARP10 (0.46) | FAAHKDM4ESMN1; SMN2MAOBPARP10 | |
| SCHEMBL27734528 | 0.67 | PARP10 (0.46) | FAAHKDM4ESMN1; SMN2MAOBPARP10 | |
| Hydrochloric Acid SCHEMBL8865813 | 0.67 | DRD2 (0.46) | PLA2G7FAAH | |
| SCHEMBL7115531 | 0.66 | KDM4E (0.54) | FAAHKDM4ESMN1; SMN2MAOBPARP10 | |
| SCHEMBL30530685 | 0.66 | KDM4E (0.53) | FAAHKDM4ESMN1; SMN2MAOBPARP10 | |
| SCHEMBL6783763 | 0.64 | SPHK1 (0.42) | FAAHMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8865807 | 0.64 | PLA2G7 (0.38) | PLA2G7MAOB | |
| SCHEMBL13251237 | 0.64 | TDP1 (0.53) | FAAHKDM4ESMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691358-A | IMAGING 5-HT2-RECEPTOR SITES, RADIOLABELED | JANSSEN PHARMACEUTICA, N.V. (BE) | 1997-11-25 | — | — | US | disclosed |
| US-5688814-A | MARKING 5HT2 RECEPTORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1997-11-18 | — | — | US | disclosed |