Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8865813 | 0.74 | DRD2 (0.46) | DRD2DRD4DRD3USP2ALDH1A1 | |
| SCHEMBL5238412 | 0.68 | SSTR5 (0.39) | DRD2DRD3PLA2G7LMNA | |
| SCHEMBL10338308 | 0.68 | MEN1 (0.60) | DRD2DRD4DRD3USP2ALDH1A1 | |
| SCHEMBL16809146 | 0.68 | HTR1B (0.66) | DRD2DRD4DRD3USP2ALDH1A1 | |
| SCHEMBL8866372 | 0.67 | PLA2G7 (0.40) | FAAHPLA2G7MEN1HTTKMT2A | |
| SCHEMBL8329060 | 0.67 | MEN1 (0.45) | DRD2DRD4DRD3USP2ALDH1A1 | |
| SCHEMBL5753026 | 0.67 | HRH1 (0.65) | DRD2DRD3USP2ALDH1A1HPGD | |
| SCHEMBL4270834 | 0.66 | TSHR (0.64) | DRD2DRD4DRD3USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8865807 | 0.66 | PLA2G7 (0.38) | DRD2DRD3USP2ALDH1A1HPGD | |
| SCHEMBL8484170 | 0.66 | HTR1A (0.54) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842174-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING MYOCARDIAL ISCHAEMIA | PIERRE FABRE MEDICAMENT (FR) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005134-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING MYOCARDIAL ISCHAEMIA | PIERRE FABRE MEDICAMENT (FR) | 1997-02-13 | — | — | WO | disclosed |