Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866087 | 0.90 | GFER (0.41) | TLR9CHRM4SMN1; SMN2TP53TLR7 | |
| SCHEMBL8866743 | 0.90 | ITGB3 (0.41) | TLR9CHRM4SMN1; SMN2TP53TLR7 | |
| SCHEMBL8866419 | 0.84 | APP (0.44) | TLR9CHRM4SMN1; SMN2TP53TLR7 | |
| SCHEMBL8867328 | 0.80 | ITGB3 (0.43) | TLR9CHRM4SMN1; SMN2TP53TLR7 | |
| SCHEMBL8867277 | 0.79 | EGLN1 (0.46) | CHRM4SMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL8867456 | 0.78 | CHRM4 (0.46) | CHRM4SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8865847 | 0.75 | CA2 (0.41) | CHRM4SMN1; SMN2SCDNPC1RAB9A | |
| SCHEMBL8866561 | 0.75 | CA2 (0.41) | CHRM4SMN1; SMN2SCDNPC1RAB9A | |
| SCHEMBL8866386 | 0.75 | SUV39H2 (0.39) | TLR9CHRM4SMN1; SMN2TP53TLR7 | |
| SCHEMBL8866504 | 0.74 | APP (0.43) | TLR9CHRM4SMN1; SMN2TP53TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |