Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 5/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865847 | 1.00 | CA2 (0.41) | CA2CA1HDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8866374 | 0.90 | TMPRSS15 (0.47) | CA2CA1HDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8867298 | 0.90 | TMPRSS15 (0.47) | CA2CA1HDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8866459 | 0.85 | ALDH1A3 (0.43) | CA2CA1HDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8866186 | 0.85 | ALDH1A3 (0.43) | CA2CA1HDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8867277 | 0.83 | EGLN1 (0.46) | HDAC1ALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8867456 | 0.81 | CHRM4 (0.46) | CA2CA1HDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8866087 | 0.76 | GFER (0.41) | HDAC1ALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8866475 | 0.75 | TLR9 (0.41) | HDAC1ALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8866164 | 0.74 | SUV39H2 (0.43) | ALDH1A1SMN1; SMN2KDM4ENPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |