Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 10/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 3/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | ACACA | Q13085 | 2/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866485 | 0.89 | ACACB (0.42) | WDR5CKS1BSKP1SKP2AURKA | |
| SCHEMBL8866627 | 0.78 | IRAK1 (0.45) | USP30WDR5CKS1BSKP1SKP2 | |
| SCHEMBL8866813 | 0.75 | ACACB (0.51) | WDR5CKS1BSKP1SKP2ACACB | |
| SCHEMBL8866617 | 0.74 | ACACB (0.51) | CKS1BSKP1SKP2ACACBACACA | |
| Trifluoroacetic Acid SCHEMBL8866732 | 0.73 | WDR5 (0.42) | WDR5HPGDS | |
| SCHEMBL8867021 | 0.72 | ACACB (0.50) | WDR5CKS1BSKP1SKP2ACACB | |
| SCHEMBL8866628 | 0.70 | GNA11 (0.37) | WDR5HPGDSACACBACACASCN9A | |
| SCHEMBL8866821 | 0.70 | WDR5 (0.45) | USP30WDR5 | |
| SCHEMBL8866094 | 0.70 | ACACB (0.45) | CKS1BSKP1SKP2ACACBACACA | |
| SCHEMBL16003606 | 0.69 | PDE10A (0.58) | CKS1BSKP1SKP2HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |