Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296592 | 0.86 | ATM (0.66) | ATMKDM4ECA2CA12CA1 | |
| SCHEMBL8867447 | 0.85 | CALM1 (0.67) | ATMKDM4ECALM1CA2CA12 | |
| SCHEMBL8866713 | 0.83 | ATM (0.50) | ATMKDM4ECALM1CA2POLB | |
| SCHEMBL9178046 | 0.81 | FFAR4 (0.55) | POLBSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL5978889 | 0.80 | ALDH1A1 (0.53) | KDM4ECA2POLBCYP3A4SMN1; SMN2 | |
| SCHEMBL1734396 | 0.79 | KDM4E (0.53) | ATMKDM4ECALM1CA2POLB | |
| SCHEMBL6301878 | 0.79 | POLB (0.56) | ATMKDM4ECALM1CA2CA12 | |
| SCHEMBL9175204 | 0.78 | PPARA (0.58) | POLBSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL14586637 | 0.78 | ATM (0.51) | ATMKDM4ECALM1CA2POLB | |
| SCHEMBL6566769 | 0.78 | CA5A (0.62) | KDM4ECA5ACYP1A2CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |