Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | CCR8 | P51685 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866951 | 0.89 | CCR8 (0.43) | DRD3CCR8KCNH2TP53THRB | |
| SCHEMBL6178837 | 0.82 | MEN1 (0.54) | LMNASMN1; SMN2HSD17B10POLBTBK1 | |
| SCHEMBL8866404 | 0.78 | GPR119 (0.40) | CCR8KCNH2LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL19966525 | 0.78 | CCNT1 (0.49) | CCR8KCNH2LMNASMN1; SMN2GABRP | |
| SCHEMBL28226884 | 0.76 | MEN1 (0.55) | CCR8KCNH2POLBGABRPGABRD | |
| SCHEMBL8867058 | 0.76 | CYP1A2 (0.47) | LMNASMN1; SMN2HSD17B10GABRPGABRD | |
| SCHEMBL7498578 | 0.76 | LMNA (0.49) | CCR8KCNH2LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL9234644 | 0.74 | RBP4 (0.40) | CCR8KCNH2LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL8866585 | 0.73 | SMYD3 (0.46) | LMNASMN1; SMN2GABRPGABRDGABRA1 | |
| SCHEMBL30963390 | 0.73 | CRBN (0.47) | DRD3KCNH2LMNASMN1; SMN2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |