Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 11/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9229598 | 0.89 | SUV39H2 (0.42) | SUV39H2HDAC1 | |
| SCHEMBL8866736 | 0.89 | ALDH1A1 (0.41) | ALDH1A1MAPK1SMN1; SMN2THRBHTR1A | |
| SCHEMBL8867482 | 0.83 | SUV39H2 (0.47) | SUV39H2ALDH1A1HDAC1 | |
| SCHEMBL8866643 | 0.83 | SUV39H2 (0.47) | SUV39H2ALDH1A1HDAC1 | |
| SCHEMBL8866447 | 0.82 | SUV39H2 (0.46) | SUV39H2SMN1; SMN2THRBTP53 | |
| SCHEMBL8866022 | 0.80 | SUV39H2 (0.40) | SUV39H2 | |
| SCHEMBL8866874 | 0.80 | SUV39H2 (0.44) | SUV39H2ALDH1A1THRBTP53 | |
| SCHEMBL8866849 | 0.80 | SUV39H2 (0.44) | SUV39H2ALDH1A1THRBTP53 | |
| SCHEMBL8866503 | 0.78 | TP53 (0.42) | SUV39H2THRBTP53 | |
| SCHEMBL9234782 | 0.77 | HPGDS (0.40) | SUV39H2ALDH1A1MAPK1SMN1; SMN2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |