Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866952 | 1.00 | MAPT (0.46) | MAPTMAOAMAOBSLC6A19MTNR1B | |
| SCHEMBL8868109 | 0.89 | MAPT (0.60) | MAPTEPHX1PKMMEN1KMT2A | |
| SCHEMBL8868106 | 0.89 | MAPT (0.60) | MAPTEPHX1PKMMEN1KMT2A | |
| SCHEMBL8866966 | 0.89 | MAPT (0.46) | MAPTMAOAMAOBSLC6A19MTNR1B | |
| SCHEMBL8867206 | 0.87 | EPHX1 (0.56) | MAPTCDK8EPHX1PKMSMN1; SMN2 | |
| SCHEMBL8867201 | 0.87 | EPHX1 (0.56) | MAPTCDK8EPHX1PKMSMN1; SMN2 | |
| SCHEMBL8867734 | 0.86 | MAOA (0.44) | MAPTMAOAMAOBEPHX1PKM | |
| SCHEMBL8867739 | 0.86 | MAOA (0.44) | MAPTMAOAMAOBEPHX1PKM | |
| SCHEMBL8867679 | 0.86 | MAOB (0.46) | MAPTMAOAMAOBPKMMEN1 | |
| SCHEMBL8867682 | 0.86 | MAOB (0.46) | MAPTMAOAMAOBPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |