Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867739 | 1.00 | MAOA (0.44) | MAOAMAOBPKMMEN1KMT2A | |
| SCHEMBL8867748 | 0.89 | FGFR3 (0.45) | MAOAMAOBPKMMEN1KMT2A | |
| SCHEMBL8866952 | 0.86 | MAPT (0.46) | MAOAMAOBPKMMEN1KMT2A | |
| SCHEMBL8866959 | 0.86 | MAPT (0.46) | MAOAMAOBPKMMEN1KMT2A | |
| SCHEMBL8867288 | 0.84 | MAOB (0.53) | MAOAMAOBPKMMEN1KMT2A | |
| SCHEMBL8867284 | 0.84 | MAOB (0.53) | MAOAMAOBPKMMEN1KMT2A | |
| SCHEMBL8868109 | 0.84 | MAPT (0.60) | PKMMEN1KMT2AMAPTHTT | |
| SCHEMBL8867047 | 0.84 | GAA (0.44) | MAOAMAOBPKMMEN1KMT2A | |
| SCHEMBL8868106 | 0.84 | MAPT (0.60) | PKMMEN1KMT2AMAPTHTT | |
| SCHEMBL8867054 | 0.84 | GAA (0.44) | MAOAMAOBPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |