Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867206 | 1.00 | EPHX1 (0.56) | EPHX1ALDH1A1HTTMAPTEPHX2 | |
| SCHEMBL8868106 | 0.92 | MAPT (0.60) | EPHX1ALDH1A1HTTMAPTEPHX2 | |
| SCHEMBL8868109 | 0.92 | MAPT (0.60) | EPHX1ALDH1A1HTTMAPTEPHX2 | |
| SCHEMBL8867211 | 0.90 | EPHX1 (0.56) | EPHX1ALDH1A1HTTMAPTEPHX2 | |
| SCHEMBL8866952 | 0.87 | MAPT (0.46) | EPHX1MAPTPKMCDK8SMN1; SMN2 | |
| SCHEMBL8866959 | 0.87 | MAPT (0.46) | EPHX1MAPTPKMCDK8SMN1; SMN2 | |
| SCHEMBL8868116 | 0.82 | MAPT (0.60) | EPHX1ALDH1A1HTTMAPTEPHX2 | |
| SCHEMBL8867734 | 0.82 | MAOA (0.44) | EPHX1ALDH1A1HTTMAPTPKM | |
| SCHEMBL8867739 | 0.82 | MAOA (0.44) | EPHX1ALDH1A1HTTMAPTPKM | |
| SCHEMBL8867679 | 0.81 | MAOB (0.46) | ALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |