Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.53 |
| ▸ | SNCA | P37840 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867042 | 1.00 | KCNK3 (0.59) | KCNK3SMN1; SMN2PKMHTTKCNK9 | |
| SCHEMBL8867045 | 0.90 | KCNK3 (0.59) | KCNK3SMN1; SMN2PKMHTTKCNK9 | |
| SCHEMBL8868832 | 0.86 | KCNK3 (0.62) | KCNK3SMN1; SMN2PKMHTTL3MBTL1 | |
| SCHEMBL8868829 | 0.86 | KCNK3 (0.62) | KCNK3SMN1; SMN2PKMHTTL3MBTL1 | |
| SCHEMBL8866994 | 0.84 | PKM (0.54) | KCNK3SMN1; SMN2PKMKCNK9SNCA | |
| SCHEMBL8866601 | 0.84 | L3MBTL1 (0.70) | KCNK3PKMKCNK9SNCAL3MBTL1 | |
| SCHEMBL8867822 | 0.84 | SNCA (0.68) | KCNK3SMN1; SMN2PKMKCNK9SNCA | |
| SCHEMBL8866986 | 0.84 | PKM (0.54) | KCNK3SMN1; SMN2PKMKCNK9SNCA | |
| SCHEMBL8867810 | 0.84 | SNCA (0.68) | KCNK3SMN1; SMN2PKMKCNK9SNCA | |
| SCHEMBL8867765 | 0.84 | HDAC3 (0.54) | KCNK3SMN1; SMN2PKMKCNK9SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |