Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867284 | 1.00 | MAOB (0.53) | MAOBMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL8867605 | 0.89 | MMP1 (0.47) | MAOBMEN1KMT2AMAOAPKM | |
| SCHEMBL8867610 | 0.89 | MMP1 (0.47) | MAOBMEN1KMT2AMAOAPKM | |
| SCHEMBL8867294 | 0.88 | MAOB (0.53) | MAOBMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL8867682 | 0.87 | MAOB (0.46) | MAOBMEN1KMT2AMAPTMAOA | |
| SCHEMBL8867757 | 0.87 | ALDH1A1 (0.49) | MAOBMEN1KMT2AMAPTHTT | |
| SCHEMBL8867056 | 0.87 | KMT2A (0.51) | MAOBMEN1KMT2AMAPTLMNA | |
| SCHEMBL8867062 | 0.87 | KMT2A (0.51) | MAOBMEN1KMT2AMAPTLMNA | |
| SCHEMBL8867679 | 0.87 | MAOB (0.46) | MAOBMEN1KMT2AMAPTMAOA | |
| SCHEMBL8867761 | 0.87 | ALDH1A1 (0.49) | MAOBMEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |