Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | DDX3X | O00571 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867761 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MAOBMAOAPKMDDX3X | |
| SCHEMBL8867284 | 0.87 | MAOB (0.53) | MAOBMAOAPKMMEN1KMT2A | |
| SCHEMBL8867288 | 0.87 | MAOB (0.53) | MAOBMAOAPKMMEN1KMT2A | |
| SCHEMBL8867682 | 0.85 | MAOB (0.46) | ALDH1A1MAOBMAOAPKMMEN1 | |
| SCHEMBL8867679 | 0.85 | MAOB (0.46) | ALDH1A1MAOBMAOAPKMMEN1 | |
| SCHEMBL8866952 | 0.83 | MAPT (0.46) | MAOBMAOAPKMMEN1KMT2A | |
| SCHEMBL8866959 | 0.83 | MAPT (0.46) | MAOBMAOAPKMMEN1KMT2A | |
| SCHEMBL8867739 | 0.83 | MAOA (0.44) | ALDH1A1MAOBMAOAPKMMEN1 | |
| SCHEMBL8867734 | 0.83 | MAOA (0.44) | ALDH1A1MAOBMAOAPKMMEN1 | |
| SCHEMBL8867857 | 0.82 | CA1 (0.51) | ALDH1A1MAOBMAOAPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |