Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 8/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865843 | 0.97 | ACACB (0.36) | HDAC4HDAC6SCN9ASCN3ASCN5A | |
| SCHEMBL8866833 | 0.81 | CA12 (0.38) | HDAC4HDAC6SCN9ASCN3ASCN5A | |
| SCHEMBL8867154 | 0.78 | TTK (0.38) | HDAC4HDAC6SCN9ASCN3ASCN5A | |
| SCHEMBL8867351 | 0.77 | ATR (0.38) | GPR119TTKHDAC1 | |
| SCHEMBL8866062 | 0.76 | ACACB (0.43) | GPR119TTK | |
| SCHEMBL8865697 | 0.76 | TTK (0.39) | TTK | |
| SCHEMBL8866628 | 0.74 | GNA11 (0.37) | SCN9ASCN3ASCN5AGPR119GNA11 | |
| SCHEMBL8867167 | 0.74 | ACACB (0.34) | HDAC4HDAC6SCN9ASCN3ASCN5A | |
| SCHEMBL8867162 | 0.72 | ACACB (0.38) | TTK | |
| SCHEMBL8867355 | 0.70 | CHRM1 (0.41) | SCN9ASCN3ASCN5AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |