Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNA11 | P29992 | 2/20 | 0.37 |
| ▸ | GNAQ | P50148 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 3/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866091 | 0.80 | WDR5 (0.40) | CHEK1GPR119ACACBACACAWDR5 | |
| SCHEMBL8866110 | 0.80 | ACACB (0.41) | GNA11GNAQGPR119ACACBACACA | |
| SCHEMBL8866485 | 0.80 | ACACB (0.42) | CHEK1ACACBACACAWDR5 | |
| SCHEMBL8865843 | 0.79 | ACACB (0.36) | GNA11GNAQGPR119ACACBACACA | |
| SCHEMBL8866516 | 0.78 | WDR5 (0.40) | CHEK1GPR119ACACBACACAWDR5 | |
| SCHEMBL8867154 | 0.77 | TTK (0.38) | GNA11GNAQACACBACACASCN9A | |
| SCHEMBL8866377 | 0.77 | ACACB (0.38) | GNA11GNAQGPR119ACACBACACA | |
| SCHEMBL8866617 | 0.77 | ACACB (0.51) | ACACBACACA | |
| SCHEMBL8867351 | 0.76 | ATR (0.38) | GPR119ACACBACACA | |
| SCHEMBL8865697 | 0.75 | TTK (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614531-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |