Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.51 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867103 | 0.84 | TARBP2 (0.70) | TARBP2MCL1KDM4ERAB9AGAA | |
| SCHEMBL8867840 | 0.84 | CDC7 (0.57) | CDC7DBF4TARBP2MCL1KDM4E | |
| SCHEMBL15049250 | 0.82 | RAB9A (0.68) | CDC7DBF4CCNE1CDK2TARBP2 | |
| SCHEMBL4163499 | 0.82 | SMN1; SMN2 (0.64) | CDC7DBF4CCNE1CDK2KDM4E | |
| SCHEMBL3419091 | 0.75 | RAB9A (0.74) | TARBP2KDM4ERAB9AGAAXDH | |
| SCHEMBL17374857 | 0.74 | CDC7 (0.55) | CDC7DBF4CCNE1CDK2KDM4E | |
| SCHEMBL5192459 | 0.73 | PTGDR2 (0.53) | CDC7DBF4TARBP2KDM4ERAB9A | |
| SCHEMBL3769265 | 0.73 | PTGDR2 (0.53) | TARBP2KDM4ERAB9AGAAPTGDR2 | |
| SCHEMBL17374846 | 0.72 | CDC7 (0.52) | CDC7DBF4CCNE1CDK2KDM4E | |
| SCHEMBL17374804 | 0.71 | TRPM8 (0.59) | CDC7DBF4CCNE1CDK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614520-A | 2-arylthiazole derivatives and pharmaceutical composition thereof | TEIJIN LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0513379-B1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0513379-A1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1992-11-19 | — | — | EP | disclosed |