Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | CDC7 | O00311 | 5/20 | 0.60 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.60 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.60 |
| ▸ | CDK2 | P24941 | 2/20 | 0.60 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15049250 | 0.88 | RAB9A (0.68) | SMN1; SMN2CDC7DBF4CCNE1CDK2 | |
| SCHEMBL17374804 | 0.84 | TRPM8 (0.59) | SMN1; SMN2CDC7DBF4CCNE1CDK2 | |
| SCHEMBL4163787 | 0.83 | CDC7 (0.79) | CDC7DBF4TRPM8ALOX5ALDH1A1 | |
| SCHEMBL8867386 | 0.82 | CDC7 (0.51) | SMN1; SMN2CDC7DBF4CCNE1CDK2 | |
| SCHEMBL15049460 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2CDC7DBF4TRPM8ALOX5 | |
| SCHEMBL1327631 | 0.78 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HPGDNPSR1GAA | |
| SCHEMBL27500256 | 0.77 | SMN1; SMN2 (0.59) | SMN1; SMN2CDC7DBF4TRPM8ALDH1A1 | |
| SCHEMBL15048961 | 0.76 | CDC7 (0.73) | SMN1; SMN2CDC7DBF4CCNE1CDK2 | |
| SCHEMBL974859 | 0.76 | CDC7 (0.84) | SMN1; SMN2CDC7DBF4CCNE1CDK2 | |
| SCHEMBL13802657 | 0.76 | HRH3 (0.57) | ALOX5ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470816-B2 | Nitrogen-containing heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-06-25 | — | — | US | disclosed |
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | NTSR2, NTSR1, HNMT | SMN1; SMN2 1425/4885CDC7 3202/4885DBF4 2822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.