Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.71 |
| ▸ | RAB9A | P51151 | 7/20 | 0.71 |
| ▸ | CCR5 | P51681 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.54 |
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868321 | 0.87 | CACNA1B (0.63) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL25815514 | 0.87 | NPC1 (0.71) | NPC1RAB9ACCR5SMN1; SMN2MAPT | |
| SCHEMBL8361574 | 0.87 | NPC1 (0.71) | NPC1RAB9ACCR5SMN1; SMN2MAPT | |
| SCHEMBL8867481 | 0.87 | NPC1 (0.71) | NPC1RAB9ACCR5SMN1; SMN2MAPT | |
| SCHEMBL8868824 | 0.87 | NPC1 (0.71) | NPC1RAB9ACCR5SMN1; SMN2MAPT | |
| SCHEMBL24935348 | 0.84 | NPC1 (0.67) | NPC1RAB9ACCR5SMN1; SMN2MAPT | |
| SCHEMBL8867185 | 0.84 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL8363015 | 0.84 | TRPV1 (0.76) | NPC1RAB9ACCR5SMN1; SMN2MAPT | |
| SCHEMBL17664553 | 0.84 | NR1H4 (0.74) | NPC1RAB9ACCR5SMN1; SMN2MAPT | |
| SCHEMBL12310125 | 0.84 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |