Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.63 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868289 | 0.90 | SMN1; SMN2 (0.57) | MEN1KMT2AALDH1A1POLBHPGD | |
| SCHEMBL8867477 | 0.87 | NPC1 (0.71) | MEN1KMT2AALDH1A1TRPV1POLB | |
| SCHEMBL8868328 | 0.87 | CACNA1B (0.63) | CACNA1BAPBA1MEN1KMT2ACYP2C9 | |
| SCHEMBL8867408 | 0.85 | KMT2A (0.59) | MEN1KMT2AALDH1A1HPGDNR1H4 | |
| SCHEMBL8867185 | 0.84 | NPC1 (0.63) | CACNA1BAPBA1MEN1KMT2AALDH1A1 | |
| SCHEMBL13210697 | 0.84 | CACNA1B (0.85) | CACNA1BAPBA1MEN1KMT2AALDH1A1 | |
| SCHEMBL8867874 | 0.84 | KMT2A (0.58) | MEN1KMT2AALDH1A1POLBHPGD | |
| SCHEMBL8867048 | 0.84 | POLB (0.71) | MEN1KMT2ATRPV1POLBNR1H4 | |
| SCHEMBL8867653 | 0.84 | MITF (0.68) | MEN1KMT2AALDH1A1POLBNPC1 | |
| SCHEMBL8867694 | 0.83 | PTPN1 (0.62) | CACNA1BAPBA1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |