Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 2/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867677 | 1.00 | PKM (0.55) | PKMKMT2AKDM4EPOLBCTDSP1 | |
| SCHEMBL8867760 | 0.89 | NPC1 (0.57) | PKMKMT2ASNCASIRT1KCNK3 | |
| SCHEMBL8867756 | 0.89 | NPC1 (0.57) | PKMKMT2ASNCASIRT1KCNK3 | |
| SCHEMBL8867605 | 0.86 | MMP1 (0.47) | PKMKMT2ASNCAMAOAMAOB | |
| SCHEMBL8867610 | 0.86 | MMP1 (0.47) | PKMKMT2ASNCAMAOAMAOB | |
| SCHEMBL8867288 | 0.85 | MAOB (0.53) | PKMKMT2APOLBSNCASIRT1 | |
| SCHEMBL8867284 | 0.85 | MAOB (0.53) | PKMKMT2APOLBSNCASIRT1 | |
| SCHEMBL8867022 | 0.83 | MMP1 (0.46) | MAOAMAOBMMP1MMP2MMP9 | |
| SCHEMBL8867015 | 0.83 | MMP1 (0.46) | MAOAMAOBMMP1MMP2MMP9 | |
| SCHEMBL8867406 | 0.79 | PKM (0.50) | PKMKMT2ATDP1SNCAKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |