Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 6/20 | 0.67 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.67 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | RARA | P10276 | 1/20 | 0.58 |
| ▸ | RARB | P10826 | 1/20 | 0.58 |
| ▸ | RARG | P13631 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289229 | 0.90 | CDC7 (0.73) | CDC7DBF4TRPM8LMNARARA | |
| SCHEMBL1316281 | 0.90 | CDC7 (0.77) | CDC7DBF4TRPM8LMNARARA | |
| SCHEMBL8867028 | 0.88 | CDC7 (0.71) | CDC7DBF4TRPM8LMNARARA | |
| SCHEMBL2880861 | 0.85 | CDC7 (0.67) | CDC7DBF4TRPM8LMNARARA | |
| SCHEMBL8867115 | 0.84 | SMN1; SMN2 (0.77) | LMNARARARARBRARGALDH1A1 | |
| SCHEMBL892889 | 0.84 | CDC7 (0.77) | CDC7DBF4TRPM8LMNAALDH1A1 | |
| SCHEMBL290013 | 0.84 | CDC7 (0.68) | CDC7DBF4TRPM8LMNARARA | |
| SCHEMBL290384 | 0.83 | CDC7 (0.75) | CDC7DBF4TRPM8LMNAALDH1A1 | |
| SCHEMBL257340 | 0.82 | NPC1 (0.59) | CDC7DBF4TRPM8LMNAALDH1A1 | |
| SCHEMBL2885887 | 0.82 | TRPM8 (0.78) | CDC7DBF4TRPM8LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614520-A | 2-arylthiazole derivatives and pharmaceutical composition thereof | TEIJIN LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0513379-B1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0513379-A1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1992-11-19 | — | — | EP | disclosed |