Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867720 | 1.00 | MAOB (0.43) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL8867682 | 0.85 | MAOB (0.46) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL8867679 | 0.85 | MAOB (0.46) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL8867254 | 0.83 | TP53 (0.50) | MAOBMAOAMAPTTP53PKM | |
| SCHEMBL8867246 | 0.83 | TP53 (0.50) | MAOBMAOAMAPTTP53PKM | |
| SCHEMBL8867288 | 0.83 | MAOB (0.53) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL8867284 | 0.83 | MAOB (0.53) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL8867739 | 0.82 | MAOA (0.44) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL8866952 | 0.82 | MAPT (0.46) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL8867734 | 0.82 | MAOA (0.44) | MAOBMAOAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |