Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867731 | 0.86 | TSHR (0.58) | TSHRHRH3CA12CA1CA2 | |
| SCHEMBL3678231 | 0.86 | TSHR (0.58) | TSHRHRH3CA12CA1CA2 | |
| SCHEMBL100560 | 0.83 | TSHR (0.63) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL687878 | 0.82 | TSHR (0.79) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL14468490 | 0.81 | TSHR (0.61) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL11109576 | 0.81 | TSHR (0.53) | TSHRHRH3CA12CA1CA2 | |
| SCHEMBL11112348 | 0.81 | ALDH1A1 (0.57) | TSHRNPY5R | |
| SCHEMBL11104075 | 0.81 | TSHR (0.53) | TSHRHRH3CA12CA1CA2 | |
| SCHEMBL8531301 | 0.80 | TSHR (0.59) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL11375896 | 0.80 | TSHR (0.65) | TSHRHRH3CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |