Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867765 | 1.00 | HDAC3 (0.54) | HDAC3HDAC1PKML3MBTL1MET | |
| SCHEMBL8867781 | 0.90 | HDAC3 (0.54) | HDAC3HDAC1PKML3MBTL1MET | |
| SCHEMBL8868792 | 0.87 | RAB9A (0.54) | PKML3MBTL1SNCAALDH1A1NPC1 | |
| SCHEMBL8867877 | 0.87 | RAB9A (0.56) | PKML3MBTL1SNCAALDH1A1NPC1 | |
| SCHEMBL8868800 | 0.87 | RAB9A (0.54) | PKML3MBTL1SNCAALDH1A1NPC1 | |
| SCHEMBL8867883 | 0.87 | RAB9A (0.56) | PKML3MBTL1SNCAALDH1A1NPC1 | |
| SCHEMBL8866994 | 0.87 | PKM (0.54) | HDAC3HDAC1PKML3MBTL1SNCA | |
| SCHEMBL8866601 | 0.87 | L3MBTL1 (0.70) | PKML3MBTL1METPTGS2SNCA | |
| SCHEMBL8867810 | 0.87 | SNCA (0.68) | HDAC3HDAC1PKML3MBTL1MET | |
| SCHEMBL8866986 | 0.87 | PKM (0.54) | HDAC3HDAC1PKML3MBTL1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |