Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.61 |
| ▸ | IL1RN | P18510 | 1/20 | 0.61 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2822371 | 0.86 | MEN1 (0.67) | HTR6HDAC1HDAC8HDAC4MEN1 | |
| SCHEMBL8867847 | 0.85 | HTR6 (0.73) | HTR6HDAC1HDAC8HDAC4MEN1 | |
| SCHEMBL8868125 | 0.84 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL8249490 | 0.84 | HDAC1 (0.76) | HTR6HDAC1HDAC8HDAC4MEN1 | |
| SCHEMBL5830405 | 0.83 | HTR6 (1.00) | HTR6HDAC1HDAC8HDAC4MEN1 | |
| SCHEMBL20245194 | 0.83 | HTR6 (0.71) | HTR6HDAC1HDAC8HDAC4MEN1 | |
| SCHEMBL3563796 | 0.83 | HDAC1 (0.66) | HTR6HDAC1HDAC8HDAC4MEN1 | |
| SCHEMBL810795 | 0.82 | KMT2A (0.91) | HTR6MEN1KMT2AALDH1A1PKM | |
| SCHEMBL2692935 | 0.81 | HDAC1 (0.78) | HTR6HDAC1HDAC8HDAC4MEN1 | |
| SCHEMBL1405096 | 0.81 | HDAC1 (0.72) | HTR6HDAC1HDAC8HDAC4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |