Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 6/20 | 0.51 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | BLVRB | P30043 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867864 | 0.90 | RAB9A (0.59) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8868565 | 0.87 | XDH (0.51) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8867196 | 0.85 | XDH (0.58) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8866996 | 0.85 | XDH (0.72) | XDHTARBP2ABCC4ABCB11PGR | |
| SCHEMBL8868384 | 0.84 | RAB9A (0.54) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8868299 | 0.83 | XDH (0.58) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8867418 | 0.83 | SMN1; SMN2 (0.55) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8867538 | 0.83 | XDH (0.72) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8867591 | 0.81 | KMO (0.49) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL8868117 | 0.79 | KMO (0.61) | RAB9ASMN1; SMN2KDM4ENPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614520-A | 2-arylthiazole derivatives and pharmaceutical composition thereof | TEIJIN LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0513379-B1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| EP-0513379-A1 | 2-ARYLTHIAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1992-11-19 | — | — | EP | disclosed |