Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869725 | 0.91 | P4HTM (0.39) | P4HTMRAB9AALDH1A1POLBEGLN1 | |
| SCHEMBL9143059 | 0.88 | P4HTM (0.53) | P4HTMNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8869554 | 0.88 | P4HTM (0.51) | P4HTMNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8869402 | 0.87 | P4HTM (0.64) | P4HTMNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8867850 | 0.87 | P4HTM (0.54) | P4HTMNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8869623 | 0.86 | P4HTM (0.49) | P4HTMNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8867860 | 0.85 | P4HTM (0.48) | P4HTMNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8869429 | 0.85 | P4HTM (0.53) | P4HTMRAB9AALDH1A1MCL1SMN1; SMN2 | |
| SCHEMBL8869086 | 0.84 | P4HTM (0.45) | P4HTMPOLB | |
| SCHEMBL8868613 | 0.84 | RAB9A (0.50) | P4HTMNPC1RAB9AALDH1A1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |